Transition to quantitative faecal immunochemical testing from guaiac faecal occult blood testing in a fully rolled-out population-based national bowel screening programme
نویسندگان
چکیده
منابع مشابه
Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy.
BACKGROUND Screening for colorectal cancer (CRC) is widely accepted, but there is no consensus on the preferred strategy. We conducted a randomised trial comparing participation and detection rates (DR) per screenee of guaiac-based faecal occult blood test (gFOBT), immunochemical FOBT (FIT), and flexible sigmoidoscopy (FS) for CRC screening. METHODS A representative sample of the Dutch popula...
متن کاملGuaiac based faecal occult blood testing for colorectal cancer screening: an obsolete strategy?
The recent paper by Scholefield and colleagues on the 20 year follow-up of the ‘Nottingham’ randomised controlled trial of guaiac based faecal occult blood test (gFOBT) colorectal cancer (CRC) screening, reports an intention to screen benefit of 13% reduced mortality from CRC and a participant benefit of 18% reduction, in spite of offering only biennial screening and with only 60% first round p...
متن کاملInterval faecal occult blood testing in a colonoscopy based screening programme detects additional pathology.
BACKGROUND Colonoscopic based surveillance is recommended for patients at increased risk of colorectal cancer. The appropriate interval between surveillance colonoscopies remains in debate, as is the "miss rate" for colorectal cancer within such screening programmes. AIMS The main aim of this study was to determine whether a one-off interval faecal occult blood test (FOBT) facilitates the det...
متن کاملColonoscopy-controlled intra-individual comparisons to screen relevant neoplasia: faecal immunochemical test vs. guaiac-based faecal occult blood test.
BACKGROUND Guaiac-based faecal occult blood tests (g-FOBTs) are most commonly used in colorectal cancer (CRC) screening programmes. Faecal immunochemical tests (FITs) are thought to be superior. AIM To compare performance of a g-FOBT and a quantitative FIT for detection of CRCs and advanced adenomas in a colonoscopy-controlled population. METHODS We assessed sensitivity and specificity of b...
متن کاملFeasibility of immunochemical faecal occult blood testing for colorectal cancer screening in Bulgaria.
PURPOSE Colorectal carcinoma (CRC) is the second most common cancer in Europe. Screening guidelines recommend a range of screening options that include faecal occult blood tests (FOBTs). The efficacy of FOBT-based CRC screening is dependent on the participation rate, thus emphasizing the importance of the latter. This study aimed at analysing the feasibility of CRC screening with immunochemical...
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ژورنال
عنوان ژورنال: Gut
سال: 2020
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2019-320297